Lactose intolerance genetics

EDTA 1ml

or oral mucosa (eSwab)

Genetic lactose intolerance, also known as primary lactose intolerance, is a condition in which the body is unable to fully digest lactose because of low levels of the enzyme lactase. Lactase is responsible for breaking down lactose into simpler sugars that can be absorbed by the body.
Primary lactose intolerance is caused by a gradual decrease in the production of the enzyme lactase after infancy/childhood. This intolerance is found in an average of 15% of the European population.
Symptoms of genetic lactose intolerance may include bloating, diarrhea, abdominal pain, and gas after consuming lactose-containing foods or beverages.

Based on the genetic examination of a point mutation, the probability of lactose intolerance after childhood can be analysed. Individuals with a homozygous genotype CC are more likely than individuals with the heterozygous genotype CT to be lactose intolerant as an adult.