Material & Volume

Serum, 1ml

Clinical information

Agomelatin is an anti-depressive agent with melatonergic effects and is administered for the treatment of episodes of major depressions. It has a double action principle: It is a highly affined agonist regarding MT1- and MT2-melatonin receptors and a competitive antagonist of the 5HT2C-serotonin receptor, which enhances the release of the neurotransmitters noradrenalin and dopamine in certain areas of the brain. The therapeutic effect is anti-depressive, soporific and normalises the circadian rhythm. The undesirable side effects can be fatigue, nausea, swooning and undue sweating.

Type of drug: Antidepressant
Metabolism: CYP1A2, CYP2C19, CYP3A4
Half life t½: 1-2h
Steady State: 1 day
TDM: potentially useful
Additional informations: Trough level cannot be measured, Cmax only for specific indications.

More information

Related analyses



Position / Price

Position: 1065.00
Price: CHF 126.00
+ Processing fee: CHF 21.60
(per order and per day)

Executing laboratory

labor team w ag

Execution time

1 day